abstract：:For magnetic resonance, the established class of intravenous contrast media is the gadolinium-based contrast agents. In the 3 decades since initial approval, these have proven in general to be very safe for human administration. However, in 2006, a devastating late adverse reaction to administration of the less stable...

journal_title：Investigative radiology

authors： Runge VM

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the effect of structured reports (SRs) in comparison to nonstructured, free-text (FT) rectal magnetic resonance imaging (MRI) reports in patients with histologically proven rectal cancer and potential effects of both types of reporting on referring surgeons' satisfaction...

journal_title：Investigative radiology

authors： Nörenberg D,Sommer WH,Thasler W,DʼHaese J,Rentsch M,Kolben T,Schreyer A,Rist C,Reiser M,Armbruster M

更新日期：2017-04-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to optimize computed tomography (CT) surveillance of skeletal metastases in patients with breast cancer through the use of osseous subtraction maps between baseline and follow-up examinations created by a novel software algorithm. The new postprocessing algorithm segments the origina...

journal_title：Investigative radiology

authors： Horger M,Thaiss WM,Wiesinger B,Ditt H,Fritz J,Nikolaou K,Kloth C

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the potential of iterative metal artifact reduction (IMAR) for the improvement of computed tomography (CT)-based position emission tomography (PET) attenuation correction in the vicinity of metal implants and compare it with dual-energy-based metal artifact reduction stra...

journal_title：Investigative radiology

authors： Schabel C,Gatidis S,Bongers M,Hüttig F,Bier G,Kupferschlaeger J,Bamberg F,la Fougère C,Nikolaou K,Pfannenberg C

更新日期：2017-01-01 00:00:00

abstract：:Attenuation correction (AC) is an essential step in the positron emission tomography (PET) data reconstruction process to provide accurate and quantitative PET images. The introduction of PET/magnetic resonance (MR) hybrid systems has raised new challenges but also possibilities regarding PET AC. While in PET/computed...

journal_title：Investigative radiology

authors： Paulus DH,Quick HH

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to evaluate the diagnostic value of x-ray dark-field imaging in projection radiography-based depiction of pneumothoraces in the neonatal murine lung, a potentially life-threatening medical condition that requires a timely and correct diagnosis. MATERIALS AND METHODS:By the use of a ...

journal_title：Investigative radiology

authors： Hellbach K,Yaroshenko A,Willer K,Pritzke T,Baumann A,Hesse N,Auweter S,Reiser MF,Eickelberg O,Pfeiffer F,Hilgendorff A,Meinel FG

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the impact of impaired renal function on gadolinium (Gd) retention in various organs after Gd-based contrast agent injection. MATERIALS AND METHODS:After local animal care and review committee approval, 23 normal mice and 26 with renal failure were divided into 4 tre...

journal_title：Investigative radiology

authors： Kartamihardja AA,Nakajima T,Kameo S,Koyama H,Tsushima Y

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare quantitative and semiquantitative parameters (signal-to-noise ratio [SNR], contrast-to-noise ratio [CNR], image quality, diagnostic confidence) from a standard brain magnetic resonance imaging examination encompassing common neurological disorders such as demyelinating dis...

journal_title：Investigative radiology

authors： Springer E,Dymerska B,Cardoso PL,Robinson SD,Weisstanner C,Wiest R,Schmitt B,Trattnig S

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:The aims of this study were to compare 3 contrast agents and to define feasible doses for quantitative lung perfusion imaging using the dual-bolus approach in dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI). MATERIALS AND METHODS:Ten healthy volunteers (6 males, 4 females; mean age, 23.5 yea...

journal_title：Investigative radiology

authors： Veldhoen S,Oechsner M,Fischer A,Weng AM,Kunz AS,Bley TA,Köstler H,Ritter CO

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to implement and systematically evaluate the performance of a new parameter-free segmented algorithm for analysis of diffusion imaging data using a combined intravoxel incoherent motion and diffusion kurtosis imaging (IVIM-DKI) model of spin diffusion in comparison with the simple...

journal_title：Investigative radiology

authors： Wurnig MC,Kenkel D,Filli L,Boss A

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to compare F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/magnetic resonance (MR) (with and without diffusion-weighted imaging [DWI]) to F-FDG PET/computed tomography (CT), with regard to the assessment of nodal and extranodal involvement, in patients with Hodgkin lym...

journal_title：Investigative radiology

authors： Giraudo C,Raderer M,Karanikas G,Weber M,Kiesewetter B,Dolak W,Simonitsch-Klupp I,Mayerhoefer ME

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:Ferumoxytol, an intravenous iron supplement, can be used in off-label mode as a contrast agent in magnetic resonance imaging. The aim of this study was to assess whether ferumoxytol can be used as a marker of inflammation in animal models of acute and chronic inflammatory kidney diseases. MATERIAL AND METHO...

journal_title：Investigative radiology

authors： Budjan J,Neudecker S,Schock-Kusch D,Kraenzlin B,Schoenberg SO,Michaely HJ,Attenberger UI

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare changes in the signal intensity (SI) ratio of the dentate nucleus (DN) to the pons, DN to cerebrospinal fluid (CSF), and globus pallidus (GP) to thalamus on unenhanced T1-weighted magnetic resonance imaging (MRI) scans after serial injections of the macrocyclic gadolinium-...

journal_title：Investigative radiology

authors： Radbruch A,Weberling LD,Kieslich PJ,Hepp J,Kickingereder P,Wick W,Schlemmer HP,Bendszus M

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To investigate the correlation between intravoxel incoherent motion (IVIM) model-derived parameters and histologically determined microvascularity in pancreatic ductal adenocarcinomas (PDACs) and pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:From April 2013 to May 2014, 42 patients with mal...

journal_title：Investigative radiology

authors： Klau M,Mayer P,Bergmann F,Maier-Hein K,Hase J,Hackert T,Kauczor HU,Grenacher L,Stieltjes B

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To compare image quality and geometric distortion between readout-segmented diffusion-weighted imaging (rs-DWI) and selective-excitation accelerated reduced-field of view (FOV) DWI (sTX-DWI) of the prostate. MATERIALS AND METHODS:Sixty-five patients underwent 3-T MRI of the prostate including rs-DWI and sTX-...

journal_title：Investigative radiology

authors： Barth BK,Cornelius A,Nanz D,Eberli D,Donati OF

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the frequency and characteristics of artifacts in segmentation-based attenuation correction maps (μ-maps) of positron emission tomography/magnetic resonance (PET/MR) and their impact on PET interpretation and the standardized uptake value (SUV) quantification in no...

journal_title：Investigative radiology

authors： Brendle C,Schmidt H,Oergel A,Bezrukov I,Mueller M,Schraml C,Pfannenberg C,la Fougère C,Nikolaou K,Schwenzer N

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to perform phantom measurements to prove the feasibility of single-source dual-energy computed tomography (DECT) of the extremities using a volume scan mode. In addition, we, for the first time, wanted to determine which concentrations of monosodium urate (MSU) in gout and calcium p...

journal_title：Investigative radiology

authors： Diekhoff T,Kiefer T,Stroux A,Pilhofer I,Juran R,Mews J,Blobel J,Tsuyuki M,Ackermann B,Hamm B,Hermann KG

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to determine if voxel-based histogram analysis of intravoxel incoherent motion imaging (IVIM) parameters can differentiate various subtypes of renal tumors, including benign and malignant lesions. SUBJECTS AND METHODS:A total of 44 patients with renal tumors who underwent surgery a...

journal_title：Investigative radiology

authors： Gaing B,Sigmund EE,Huang WC,Babb JS,Parikh NS,Stoffel D,Chandarana H

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to develop and validate a computer-aided diagnosis (CAD) tool for automatic classification of pulmonary nodules seen on low-dose computed tomography into solid, part-solid, and non-solid. MATERIALS AND METHODS:Study lesions were randomly selected from 2 sites participating in t...

journal_title：Investigative radiology

authors： Jacobs C,van Rikxoort EM,Scholten ET,de Jong PA,Prokop M,Schaefer-Prokop C,van Ginneken B

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:The purpose of this study was to assess whether the recently developed method of grating-based x-ray dark-field radiography can improve the diagnosis of pulmonary emphysema in vivo. MATERIALS AND METHODS:Pulmonary emphysema was induced in female C57BL/6N mice using endotracheal instillation of porcine pancr...

journal_title：Investigative radiology

authors： Meinel FG,Yaroshenko A,Hellbach K,Bech M,Müller M,Velroyen A,Bamberg F,Eickelberg O,Nikolaou K,Reiser MF,Pfeiffer F,Yildirim AÖ

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:Altered systolic blood flow in the ascending aorta has been correlated with increased aortic growth in patients with bicuspid aortic valves (BAVs). We used conventional, 2-dimensional (2D) phase contrast magnetic resonance imaging (PC-MRI) to assess the relationship between altered flow and future growth in ...

journal_title：Investigative radiology

authors： Burris NS,Sigovan M,Knauer HA,Tseng EE,Saloner D,Hope MD

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to explore the impact of dynamic contrast-enhanced (DCE) computer tomography (CT) as a biomarker in metastatic renal cell carcinoma (mRCC). MATERIALS AND METHODS:Twelve patients with favorable or intermediate Memorial Sloan Kettering Cancer Center risk group and clear cell mRCC par...

journal_title：Investigative radiology

authors： Mains JR,Donskov F,Pedersen EM,Madsen HH,Rasmussen F

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to investigate and validate quantitative susceptibility mapping (QSM) for lesional iron quantification in cerebral cavernous malformations (CCMs). MATERIALS AND METHODS:Magnetic resonance imaging studies were performed in phantoms and 16 patients on a 3-T scanner. Susceptibility ...

journal_title：Investigative radiology

authors： Tan H,Liu T,Wu Y,Thacker J,Shenkar R,Mikati AG,Shi C,Dykstra C,Wang Y,Prasad PV,Edelman RR,Awad IA

更新日期：2014-07-01 00:00:00

abstract：PURPOSE:The purpose of this study was to assess the value of intravoxel incoherent motion and diffusion-weighted imaging for predicting the histologic grade of pancreatic neuroendocrine tumors (PNETs). MATERIALS AND METHODS:Forty patients with surgically diagnosed PNETs who underwent preoperative magnetic resonance im...

journal_title：Investigative radiology

authors： Hwang EJ,Lee JM,Yoon JH,Kim JH,Han JK,Choi BI,Lee KB,Jang JY,Kim SW,Nickel MD,Kiefer B

更新日期：2014-06-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the magnetic resonance prostate imaging reporting and data system (PI-RADS) for the detection of prostate cancer by the results of magnetic resonance imaging (MRI)-guided biopsy of the prostate as a reference standard. PATIENTS AND METHODS:In 55 patients who had underg...

journal_title：Investigative radiology

authors： Baur AD,Maxeiner A,Franiel T,Kilic E,Huppertz A,Schwenke C,Hamm B,Durmus T

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the use of dielectric pads for improving high spatial resolution imaging of the inner ear at 7 T. MATERIALS AND METHODS:Two sets of dielectric pads were designed using electromagnetic simulations and implemented using a deuterated suspension of barium titanate. Th...

journal_title：Investigative radiology

authors： Brink WM,van der Jagt AM,Versluis MJ,Verbist BM,Webb AG

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to achieve initial experience with non-contrast-enhanced (ne) magnetic resonance angiography (MRA) of the lower leg arteries in patients with peripheral arterial occlusive disease (PAOD) at 7 T. MATERIALS AND METHODS:Seven patients with PAOD were examined on a 7-T whole-body magnet...

journal_title：Investigative radiology

authors： Fischer A,Maderwald S,Johst S,Orzada S,Ladd ME,Umutlu L,Lauenstein TC,Kniemeyer HW,Nassenstein K

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to assess the feasibility of magnetic resonance cholangiography (MRC) using biliary-secreted gadoxetic acid at 7 T and to compare it with T2-weighted (w) MRC at 3 T. MATERIALS AND METHODS:Ten healthy volunteers were examined on a 7-T whole-body magnetic resonance system. T2...

journal_title：Investigative radiology

authors： Fischer A,Kraff O,Orzada S,Nensa F,Schäfer LC,Ladd ME,Umutlu L,Lauenstein TC

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to prospectively compare diagnostic performance and time efficiency of a double-reading paradigm in which a first-reader computer-aided detection (CAD) is followed by a fast 2-dimensional review (DR FR-CAD) with those of a double reading with second-reader CAD (SR CAD). MATER...

journal_title：Investigative radiology

authors： Iussich G,Correale L,Senore C,Hassan C,Segnan N,Campanella D,Bert A,Galatola G,Laudi C,Regge D

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis (NSF) has been related to the use of gadolinium-based contrast agents (GBCAs) in patients undergoing dialysis. The Prospective Fibrose Nephrogénique Systémique study, a French prospective study supported by the French drug regulatory agency (Agence Nationale de Sécurité du Médic...

journal_title：Investigative radiology

authors： Amet S,Launay-Vacher V,Clément O,Frances C,Tricotel A,Stengel B,Gauvrit JY,Grenier N,Reinhardt G,Janus N,Choukroun G,Laville M,Deray G

更新日期：2014-02-01 00:00:00

abstract：INTRODUCTION:Attenuation correction for magnetic resonance (MR) coils is a new challenge that came about with the development of combined MR and positron emission tomography (PET) imaging. This task is difficult because such coils are not directly visible on either PET or MR acquisitions with current combined scanners ...

journal_title：Investigative radiology

authors： Eldib M,Bini J,Calcagno C,Robson PM,Mani V,Fayad ZA

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the correlation between dynamic gadoxetic acid-enhanced magnetic resonance imaging parameters and specific uptake values (SUVs) derived from ¹⁸fluorodeoxyglucose (¹⁸F-FDG) and ⁶⁸Ga-DOTA-Tyr(3)-octreotate (⁶⁸Ga-DOTATATE) positron emission tomography/computed tomogra...

journal_title：Investigative radiology

authors： Armbruster M,Sourbron S,Haug A,Zech CJ,Ingrisch M,Auernhammer CJ,Nikolaou K,Paprottka PM,Rist C,Reiser MF,Sommer WH

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The objectives of this study were to test the feasibility of an investigational dual-channel next-generation endorectal coil (NG-ERC) in vivo, to quantitatively assess signal-to-noise ratio (SNR), and to get an impression of image quality compared with the current clinically available single-loop endorectal ...

journal_title：Investigative radiology

authors： Vos EK,Sambandamurthy S,Kamel M,McKenney R,van Uden MJ,Hoeks CM,Yakar D,Scheenen TW,Fütterer JJ

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine to what degree current compressed sensing methods are capable of accelerating clinical magnetic resonance neuroimaging sequences. METHODS:Two 2-dimensional clinical sequences were chosen for this study because of their long scan times. A pilot study was used to establish ...

journal_title：Investigative radiology

authors： Sharma SD,Fong CL,Tzung BS,Law M,Nayak KS

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the impact of oral water and intravenous furosemide challenges on blood oxygenation level-dependent magnetic resonance imaging measurements in the kidney and to examine the contribution of R2 (=1/T2) to changes in R2* (=1/T2*). MATERIALS AND METHODS:This Health Insurance ...

journal_title：Investigative radiology

authors： Vivier PH,Storey P,Chandarana H,Yamamoto A,Tantillo K,Khan U,Zhang JL,Sigmund EE,Rusinek H,Babb JS,Bubenheim M,Lee VS

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the feasibility of nonenhanced magnetic resonance angiography (MRA) of the lower extremities at 7 tesla (T). MATERIALS AND METHODS:Eight healthy volunteers were examined on a 7-T whole-body magnetic resonance system. For image acquisition, a custom-built 16-channel t...

journal_title：Investigative radiology

authors： Fischer A,Maderwald S,Orzada S,Johst S,Schäfer LC,Ladd ME,Nassenstein K,Umutlu L,Lauenstein TC

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Volumetric magnetic resonance (MR)-guided high-intensity focused ultrasound (HIFU) is a completely noninvasive image-guided thermal ablation technique. Recently, there has been growing interest in the use of MR-HIFU for noninvasive ablation of malignant tumors. Of particular interest for noninvasive ablation...

journal_title：Investigative radiology

authors： Wijlemans JW,Deckers R,van den Bosch MA,Seinstra BA,van Stralen M,van Diest PJ,Moonen CT,Bartels LW

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the diagnostic performance and safety of magnetic resonance (MR) imaging-guided percutaneous mediastinal biopsy procedures using a 0.23-T open MR system with optical tracking navigation. MATERIALS AND METHODS:A retrospective analysis of 59 participants (38 males an...

journal_title：Investigative radiology

authors： Lü Y,Fritz J,Li C,Liu M,Lee P,Wu L,Carrino JA

更新日期：2013-06-01 00:00:00

abstract：PURPOSE:We aimed to determine whether diffusion-weighted magnetic resonance imaging, by means of the apparent diffusion coefficient (ADC), is able to guide magnetic resonance-guided biopsy in patients fit for active surveillance (AS) and identify patients harboring high-grade Gleason components not suitable for AS. MA...

journal_title：Investigative radiology

authors： Somford DM,Hoeks CM,Hulsbergen-van de Kaa CA,Hambrock T,Fütterer JJ,Witjes JA,Bangma CH,Vergunst H,Smits GA,Oddens JR,van Oort IM,Barentsz JO,MR-PRIAS Collaboration Group.

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:Intra-arterial digital subtraction angiography (IA-DSA), an invasive procedure, is the current reference examination after percutaneous transluminal angioplasty and stenting for the detection of in-stent restenosis (ISR). In this phantom study, we evaluated flat-panel angiographic computed tomography after i...

journal_title：Investigative radiology

authors： Psychogios MN,Schramm P,Amelung N,Pilgram-Pastor SM,Gröschel K,Wasser K,Frölich AM,Mohr A,Knauth M

更新日期：2013-02-01 00:00:00